There is significant adoption of innovative technology in biotechnology which contributes to the global downstream processing market. Downstream processing refers to the purification and recovery of biosynthetic products, especially in pharmaceuticals from living organisms which includes tissues of animals or plants or fermentation broth. Downstream processing includes the recycling of those components that can be retrieved along with the treatment of disposal of wastage. It is helpful in the manufacturing of antibodies (infliximab and abciximab), antibiotics, natural hormones that are useful in the development of human growth, preparing insulin, vaccine, flavor, natural fragrance compounds, and in the production of industrial enzymes. The global rise in lethal diseases such as dengue, hepatitis, cholera, swine flu and so on will increase the demand for effective vaccination for these fatal diseases.
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The growing biotechnology sector is the major factor propelling the demand for the market. The rise in the downstream processing market is also attributed to the high adoption of biotech processing majorly in the agricultural, pharmaceutical and bio service. Rising demand for the high yield variety of seeds and other advancement is due to the development in the field of genetic engineering and gene therapy. Major players of global downstream processing industry endeavor to streamline the process and try to cut down the overall cost associated with the procedural cost and raw material which will ultimately reduce the overall price of the products.
R&D investments are on the rise and the evolution of new downstream processing technology will further help in the development of the market. However, product life degradation, regulatory directives, and strict licensing policies can be a restraint for the downstream processing market. Major downstream processing techniques include member affinity chromatography, employment of high throughput process development, perfusion chromatography, and single-use systems. Moreover, growing investment in the development of bioprocess and fermentation technology for supporting large level production of biologics and biosimilar is expected to boost the growth of the downstream processing market.
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Scope of inducing downstream processing technique for the commercial production of the biodegradable material has been increasing, owing to the development of the biosimilar. Contract Manufacturing Organizations (CMOs) are playing a distinctive role in the overall development of the market. A new pharma plant, that is equipped with the large stainless-steel bioreactor to produce large-volume biopharmaceuticals is expensive and time-consuming. Therefore, new market entrants, including startups and some large companies in their expansion programs are switching to CMOS rather than acquiring their own production house.
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The global downstream processing market is further analyzed on the basis of geographical regions, including North America, Europe, Asia-Pacific and Rest of the World. North America held a dominant position in the global downstream processing market in 2018. This is mainly owing to well-established healthcare infrastructure and the presence of key players in the region such as 3M, General Electric Co., and Thermo Fisher Scientific Inc.
The key players operating in the global downstream processing market include 3M Co., Asahi Kasei Medical Co., Ltd., Boehringer Ingelheim International GmbH, Eppendorf AG, General Electric Co., Merck KGaA, and Sartorius AG, among others. For instance, in November 2018, FUJIFILM Diosynth Biotechnologies U.S.A., Inc. collaborated with UK-based research center, the Centre for Process Innovation (CPI), for a biotechnology industry project “AMECRYS”.
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The global downstream processing market report summarizes the positive growth rate in upcoming years, and market size with competitive analysis. Our experts have analyzed the historical data to compare with the current market scenario to calculate the market growth in the coming years. The study provides an exhaustive report that includes an executive summary, scope, and forecast of the market.
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